› SynBio at a global scale: from the Petri dish to planet Earth - Victor de Lorenzo, Systems Biology Program, National Center for Biotechnology
09:00-09:30 (30min)
› Addressable Phase-separated RNAs in E. coli - Ariel Lindner, Systems Engineering and Evolution Dynamics U1284
09:30-10:00 (30min)
› Synthetic toxin-intein combinations as genetic weapons for specific killing of pathogenic bacteria in complex populations. - Didier MAZEL, Bacterial Genome Plasticity, Institut Pasteur (France)
10:30-10:50 (20min)
› A synthetic communication system uncovers self-jamming of M13 transmission - Amit Pathania, Molecular Microbiology of Actinobacteria, CNRS (France)
11:10-11:30 (20min)
› Exotic and xenobiotic deviations from the set of canonical nucleotides - Valérie Pezo, UMR 8030 LiSSB
11:30-11:50 (20min)
› Implementation of a synthetic formate assimilation pathway in Escherichia coli by adaptive evolution - Madeleine Bouzon Bloch, Génomique métabolique, CEA UMR Génomique Métabolique
11:50-12:10 (20min)
› Shape control of minimal cells by reconstitution of Spiroplasma citri cytoskeleton - Bastien Lambert, Bio 2.0, Soft Micro Systems, CNRS (France)
14:00-14:20 (20min)
› Function: the concept that (almost) everyone uses but no one really knows - and why it matters - Alberto MOLINA PEREZ, Institute for advanced social studies, Spanish National Research Council
14:50-15:20 (30min)
› Anti-CRISPR protein technologies for precision genome editing - Dominik Niopek, Technical University of Darmstadt
15:50-16:20 (30min)
› Improving CAR-T cell safety and efficacy through computational protein design - Leo Scheller, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne
16:20-16:50 (30min)
› Photocaged Transcriptional Activators for Optogenetic Gene Expression Control - Nicholas Southern, Technical University of Darmstadt
16:50-17:10 (20min)
› Towards the computational design of genetically encodable nanomachines - Alexis Courbet, University Of Washington, Institute for Protein Design
09:30-10:00 (30min)
› A deep unsupervised language model for protein design - Noelia Ferruz, University of Girona, University of Bayreuth
10:00-10:30 (30min)
› Artificial Metabolic Networks: enabling neural computations with metabolic networks - Leon Faure, Université Paris-Saclay
10:30-10:50 (20min)
› Design and implementation of de novo biosynthetic cascades for organic synthesis - Sabine Flitsch, The University of Manchester
11:20-11:50 (30min)
› Latent Dirichlet Allocation for Double Clustering (LDA-DC): Discovering patients phenotypes and cell populations within a single Bayesian framework - Elie-Julien El hachem, Sorbonne University, INSERM, Nutrition and Obesities: systemic approaches, NutriOmique, 91 Boulevard de l'hôpital, 75013 Paris, France
11:50-12:10 (20min)
› Towards engineering a native bacterial microcompartment system in Escherichia coli. - Denis Jallet, Toulouse Biotechnology Institute
14:00-14:20 (20min)
› Paclitaxel Causes Cardiac Failure by Inhibiting Voltage-Gated Potassium Current: Insight from an In Silico Study - Chitaranjan Mahapatra, Paris-Saclay Institute of Neuroscience
14:20-14:40 (20min)
› Protein Design with Automated Reasoning and Deep Learning - Marianne Defresne, Institut National des Sciences Appliquées
14:40-15:00 (20min)
Natural Product discovery and Metabolic engineering
› Scalable microbial metabolite discovery through synthetic biology - Vincent Libis, Université Paris Cité, Inserm, System Engineering and Evolution Dynamics, Paris
15:30-16:00 (30min)
› The Automated Galaxy-SynBioCAD Pipeline for Synthetic Biology Design and Engineering - Joan Herisson, Génoscope UMR 8230, University of Paris-Saclay - Evry
16:00-16:20 (20min)
› Building a synthetic cell via evolution - Christophe Danelon, TU Delft
08:30-09:00 (30min)
› A New Spin on Efficient Reconstitution of Biological Systems in GUVs - Kristina Ganzinger, AMOLF, Amsterdam
09:00-09:30 (30min)
› Cell-free biosynthesis combined with deep learning accelerates de novo development of antimicrobial peptides - Amir Pandi, Max Planck Institute for Terrestrial Microbiology
09:30-09:50 (20min)
› Enzyme reactions in coacervates droplets as artificial membraneless organelles - Nicolas Martin, Centre de Recherche Paul Pascal
09:50-10:10 (20min)
› PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H2O2 as Signal Integrator - Paul Soudier, MICrobiologie de lÁLImentation au Service de la Santé, Centre de Biochimie Structurale [Montpellier]
10:30-10:50 (20min)
› Optimized cell-free protein synthesis using unprotected linear dna from exonuclease-deficient cellular extracts - Angelo Cardoso Batista, MICrobiologie de lÁLImentation au Service de la Santé
10:50-11:10 (20min)
› Electricia coli - Paul Weimer, Evry_Paris-Saclay IGEM team
11:30-11:45 (15min)
› The CO2CURE project: Development of autotrophic Streptomyces capable of producing molecules of interest such as antibiotics by carbon fixation - Kenza BEAUNOL, iGEM team GO_Paris-Saclay - Nathan JOYET, iGEM team GO_Paris-Saclay - Raphaël VATIN, iGEM team GO_Paris-Saclay - Mahnaz SABETI AZAD, MICALIS, iGEM team GO_Paris-Saclay
11:45-12:00 (15min)
› The NAWI Project - Bastien Camillo, iGEM Team Sorbonne_U_Paris - Jeanne Gallix, iGEM Team Sorbonne_U_Paris - Luca Donati, iGEM Team Sorbonne_U_Paris - Vitushanie Yogaranjan, iGEM Team Sorbonne_U_Paris
12:15-12:30 (15min)
› Lighting up the future of agriculture: Fiat Lux, a biosynthetic tool to track pathogenic bacteria in plants - Madeleine Bourseul, Student
12:30-12:45 (15min)
› A synthetic biology toolkit to interface genetic circuits with electronics - Louise Destouches, Centre de Recherches Interdisciplinaires [Paris] - Florence Heng, Centre de Recherches Interdisciplinaires [Paris]
12:45-13:00 (15min)
Workshop - Synthetic Biology of lactic acid bacteria (Tools for LAB engineering)
› Use of recombinant Lactic Acid Bacteria to treat infectious diseases: a focus on human papillomavirus (HPV)-induced cancer - LUIS BERMUDEZ, Institut MICALIS, INRAE
14:15-14:30 (15min)
› Genetic toolbox for lactic acid bacteria - Elsa FRISTOT, Centre de Biochimie Structurale [Montpellier]
14:30-14:45 (15min)
› Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic Lactobacillus - Marc Blanch Asensio, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken) - Sourik Dey, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken)
14:45-15:00 (15min)
› The pSIP-system as a tool for genetic engineering of Lactobacillales - Kamilla Wiull, Norwegian University of Life Sciences
15:00-15:15 (15min)
› The phage mv4 recombination system: towards a reprogrammable tool for bacterial genome engineering? - Kevin Debatisse, BLADE - Bacterial Adaptation, Diversity and Engineering
15:15-15:30 (15min)
Workshop - Synthetic Biology of lactic acid bacteria (Applications of recombinant LAB)
› Potential use of recombinant biocontained lactococci to deliver the antiprotease elafin in IBD patients - Philippe langella, INRAE, Interactions des Bactéries Commensales et Probiotiques avec l\'Hôte
15:45-16:00 (15min)
› Potential and opportunities for use of recombinant lactic acid bacteria in the gut - Catherine DANIEL, "Cellular Microbiology and Physics of infection" - CIIL - U1019-UMR9017
16:00-16:15 (15min)
› Engineered Lactococcus lactis with simultaneous tumor antigen targeting and proinflammatory cytokine binding ability - Aleš Berlec, Department of Biotechnology, Jožef Stefan Institute, Faculty of Pharmacy, University of Ljubljana
16:15-16:30 (15min)
› Use of recombinant LAB as cDNA delivery vehicle and its applications - jean-marc chatel, INRAE
16:30-16:45 (15min)