Monday, September 12, 2022

Time Event (+)
08:15 - 08:45 Welcoming - Welcoming of participants and poster/presentations logistics  
08:50 - 09:00 Opening ceremony - Chairman  
09:00 - 10:50 Prokaryotic Synthetic Biology (+)  
09:00 - 09:30 › SynBio at a global scale: from the Petri dish to planet Earth - Victor de Lorenzo, Systems Biology Program, National Center for Biotechnology  
09:30 - 10:00 › Addressable Phase-separated RNAs in E. coli - Ariel Lindner, Systems Engineering and Evolution Dynamics U1284  
10:30 - 10:50 › Synthetic toxin-intein combinations as genetic weapons for specific killing of pathogenic bacteria in complex populations. - Didier MAZEL, Bacterial Genome Plasticity, Institut Pasteur (France)  
10:50 - 11:10 Coffee break  
11:10 - 12:10 Prokaryotic Synthetic Biology (+)  
11:10 - 11:30 › A synthetic communication system uncovers self-jamming of M13 transmission - Amit Pathania, Molecular Microbiology of Actinobacteria, CNRS (France)  
11:30 - 11:50 › Exotic and xenobiotic deviations from the set of canonical nucleotides - Valérie Pezo, UMR 8030 LiSSB  
11:50 - 12:10 › Implementation of a synthetic formate assimilation pathway in Escherichia coli by adaptive evolution - Madeleine Bouzon Bloch, Génomique métabolique, CEA UMR Génomique Métabolique  
12:10 - 14:00 Lunch + Poster  
14:00 - 14:50 Prokaryotic Synthetic Biology (+)  
14:00 - 14:20 › Shape control of minimal cells by reconstitution of Spiroplasma citri cytoskeleton - Bastien Lambert, Bio 2.0, Soft Micro Systems, CNRS (France)  
14:20 - 14:50 › Genomics driven discovery of anti-phage systems. - Aude Bernheim, U1284 SEED, IAME, INSERM  
14:50 - 15:20 Philosophy (+)  
14:50 - 15:20 › Function: the concept that (almost) everyone uses but no one really knows - and why it matters - Alberto MOLINA PEREZ, Institute for advanced social studies, Spanish National Research Council  
15:20 - 15:50 Coffee break + Poster session  
15:50 - 17:10 Eukaryotic Synthetic Biology (+)  
15:50 - 16:20 › Anti-CRISPR protein technologies for precision genome editing - Dominik Niopek, Technical University of Darmstadt  
16:20 - 16:50 › Improving CAR-T cell safety and efficacy through computational protein design - Leo Scheller, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne  
16:50 - 17:10 › Photocaged Transcriptional Activators for Optogenetic Gene Expression Control - Nicholas Southern, Technical University of Darmstadt  

Tuesday, September 13, 2022

Time Event (+)
09:10 - 09:30 Welcoming  
09:30 - 10:50 Molecular programming and Systems Biology (+)  
09:30 - 10:00 › Towards the computational design of genetically encodable nanomachines - Alexis Courbet, University Of Washington, Institute for Protein Design  
10:00 - 10:30 › A deep unsupervised language model for protein design - Noelia Ferruz, University of Girona, University of Bayreuth  
10:30 - 10:50 › Artificial Metabolic Networks: enabling neural computations with metabolic networks - Leon Faure, Université Paris-Saclay  
10:50 - 11:20 Coffee break + Poster session  
11:20 - 12:10 Molecular programming and Systems Biology (+)  
11:20 - 11:50 › Design and implementation of de novo biosynthetic cascades for organic synthesis - Sabine Flitsch, The University of Manchester  
11:50 - 12:10 › Latent Dirichlet Allocation for Double Clustering (LDA-DC): Discovering patients phenotypes and cell populations within a single Bayesian framework - Elie-Julien El hachem, Sorbonne University, INSERM, Nutrition and Obesities: systemic approaches, NutriOmique, 91 Boulevard de l'hôpital, 75013 Paris, France  
12:10 - 14:00 Lunch + poster  
14:00 - 15:00 Molecular programming and Systems Biology (+)  
14:00 - 14:20 › Towards engineering a native bacterial microcompartment system in Escherichia coli. - Denis Jallet, Toulouse Biotechnology Institute  
14:20 - 14:40 › Paclitaxel Causes Cardiac Failure by Inhibiting Voltage-Gated Potassium Current: Insight from an In Silico Study - Chitaranjan Mahapatra, Paris-Saclay Institute of Neuroscience  
14:40 - 15:00 › Protein Design with Automated Reasoning and Deep Learning - Marianne Defresne, Institut National des Sciences Appliquées  
15:00 - 15:30 Coffee break + Poster session  
15:30 - 16:20 Natural Product discovery and Metabolic engineering (+)  
15:30 - 16:00 › Scalable microbial metabolite discovery through synthetic biology - Vincent Libis, Université Paris Cité, Inserm, System Engineering and Evolution Dynamics, Paris  
16:00 - 16:20 › The Automated Galaxy-SynBioCAD Pipeline for Synthetic Biology Design and Engineering - Joan Herisson, Génoscope UMR 8230, University of Paris-Saclay - Evry  
16:20 - 18:00 IRN's member meeting  

Wednesday, September 14, 2022

Time Event (+)
08:00 - 08:30 Welcoming  
08:30 - 10:10 Cell-free systems and Build-a-cell (+)  
08:30 - 09:00 › Building a synthetic cell via evolution - Christophe Danelon, TU Delft  
09:00 - 09:30 › A New Spin on Efficient Reconstitution of Biological Systems in GUVs - Kristina Ganzinger, AMOLF, Amsterdam  
09:30 - 09:50 › Cell-free biosynthesis combined with deep learning accelerates de novo development of antimicrobial peptides - Amir Pandi, Max Planck Institute for Terrestrial Microbiology  
09:50 - 10:10 › Enzyme reactions in coacervates droplets as artificial membraneless organelles - Nicolas Martin, Centre de Recherche Paul Pascal  
10:10 - 10:30 Coffee break  
10:30 - 11:10 Cell-free systems and Build-a-cell (+)  
10:30 - 10:50 › PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H2O2 as Signal Integrator - Paul Soudier, MICrobiologie de lÁLImentation au Service de la Santé, Centre de Biochimie Structurale [Montpellier]  
10:50 - 11:10 › Optimized cell-free protein synthesis using unprotected linear dna from exonuclease-deficient cellular extracts - Angelo Cardoso Batista, MICrobiologie de lÁLImentation au Service de la Santé  
11:10 - 11:30 End word and poster prize - Closure ceremony  
11:30 - 13:00 Workshop - iGEM presentations (+)  
11:30 - 11:45 › Electricia coli - Paul Weimer, Evry_Paris-Saclay IGEM team  
11:45 - 12:00 › The CO2CURE project: Development of autotrophic Streptomyces capable of producing molecules of interest such as antibiotics by carbon fixation - Kenza BEAUNOL, iGEM team GO_Paris-Saclay - Nathan JOYET, iGEM team GO_Paris-Saclay - Raphaël VATIN, iGEM team GO_Paris-Saclay - Mahnaz SABETI AZAD, MICALIS, iGEM team GO_Paris-Saclay  
12:00 - 12:15 › iGEM IONIS Paris - StarchLight - Solène Galpy, Galpy - Chloé Bonef, Bonef - Alexandre Trubert, Trubert - Axelle Dieumegard, Dieumegard - Martin Pezous, Pezous  
12:15 - 12:30 › The NAWI Project - Bastien Camillo, iGEM Team Sorbonne_U_Paris - Jeanne Gallix, iGEM Team Sorbonne_U_Paris - Luca Donati, iGEM Team Sorbonne_U_Paris - Vitushanie Yogaranjan, iGEM Team Sorbonne_U_Paris  
12:30 - 12:45 › Lighting up the future of agriculture: Fiat Lux, a biosynthetic tool to track pathogenic bacteria in plants - Madeleine Bourseul, Student  
12:45 - 13:00 › A synthetic biology toolkit to interface genetic circuits with electronics - Louise Destouches, Centre de Recherches Interdisciplinaires [Paris] - Florence Heng, Centre de Recherches Interdisciplinaires [Paris]  
12:00 - 14:00 Lunch  
14:00 - 15:30 Workshop - Synthetic Biology of lactic acid bacteria (Tools for LAB engineering) (+)  
14:15 - 14:30 › Use of recombinant Lactic Acid Bacteria to treat infectious diseases: a focus on human papillomavirus (HPV)-induced cancer - LUIS BERMUDEZ, Institut MICALIS, INRAE  
14:30 - 14:45 › Genetic toolbox for lactic acid bacteria - Elsa FRISTOT, Centre de Biochimie Structurale [Montpellier]  
14:45 - 15:00 › Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic Lactobacillus - Marc Blanch Asensio, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken) - Sourik Dey, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken)  
15:00 - 15:15 › The pSIP-system as a tool for genetic engineering of Lactobacillales - Kamilla Wiull, Norwegian University of Life Sciences  
15:15 - 15:30 › The phage mv4 recombination system: towards a reprogrammable tool for bacterial genome engineering? - Kevin Debatisse, BLADE - Bacterial Adaptation, Diversity and Engineering  
15:30 - 15:45 Coffee break  
15:45 - 17:30 Workshop - Synthetic Biology of lactic acid bacteria (Applications of recombinant LAB) (+)  
15:45 - 16:00 › Potential use of recombinant biocontained lactococci to deliver the antiprotease elafin in IBD patients - Philippe langella, INRAE, Interactions des Bactéries Commensales et Probiotiques avec l\'Hôte  
16:00 - 16:15 › Potential and opportunities for use of recombinant lactic acid bacteria in the gut - Catherine DANIEL, "Cellular Microbiology and Physics of infection" - CIIL - U1019-UMR9017  
16:15 - 16:30 › Engineered Lactococcus lactis with simultaneous tumor antigen targeting and proinflammatory cytokine binding ability - Aleš Berlec, Department of Biotechnology, Jožef Stefan Institute, Faculty of Pharmacy, University of Ljubljana  
16:30 - 16:45 › Use of recombinant LAB as cDNA delivery vehicle and its applications - jean-marc chatel, INRAE