Symposium on Synthetic and Systems Biology

›8:00 (30min)

Welcoming

8:00 - 8:30 (30min)

Welcoming

›8:30 (1h40)

Cell-free systems and Build-a-cell

8:30 - 10:10 (1h40)

Cell-free systems and Build-a-cell

› Building a synthetic cell via evolution - Christophe Danelon, TU Delft 08:30-09:00 (30min)

› A New Spin on Efficient Reconstitution of Biological Systems in GUVs - Kristina Ganzinger, AMOLF, Amsterdam 09:00-09:30 (30min)

› Cell-free biosynthesis combined with deep learning accelerates de novo development of antimicrobial peptides - Amir Pandi, Max Planck Institute for Terrestrial Microbiology 09:30-09:50 (20min)

› Enzyme reactions in coacervates droplets as artificial membraneless organelles - Nicolas Martin, Centre de Recherche Paul Pascal 09:50-10:10 (20min)

›10:10 (20min)

Coffee break

10:10 - 10:30 (20min)

Coffee break

›10:30 (40min)

Cell-free systems and Build-a-cell

10:30 - 11:10 (40min)

Cell-free systems and Build-a-cell

› PeroxiHUB: A Modular Cell-Free Biosensing Platform Using H2O2 as Signal Integrator - Paul Soudier, MICrobiologie de lÁLImentation au Service de la Santé, Centre de Biochimie Structurale [Montpellier] 10:30-10:50 (20min)

› Optimized cell-free protein synthesis using unprotected linear dna from exonuclease-deficient cellular extracts - Angelo Cardoso Batista, MICrobiologie de lÁLImentation au Service de la Santé 10:50-11:10 (20min)

›11:10 (20min)

End word and poster prize

11:10 - 11:30 (20min)

End word and poster prize

Closure ceremony

›11:30 (1h30)

Workshop - iGEM presentations

11:30 - 13:00 (1h30)

Workshop - iGEM presentations

› Electricia coli - Paul Weimer, Evry_Paris-Saclay IGEM team 11:30-11:45 (15min)

› The CO2CURE project: Development of autotrophic Streptomyces capable of producing molecules of interest such as antibiotics by carbon fixation - Kenza BEAUNOL, iGEM team GO_Paris-Saclay - Nathan JOYET, iGEM team GO_Paris-Saclay - Raphaël VATIN, iGEM team GO_Paris-Saclay - Mahnaz SABETI AZAD, MICALIS, iGEM team GO_Paris-Saclay 11:45-12:00 (15min)

› iGEM IONIS Paris - StarchLight - Solène Galpy, Galpy - Chloé Bonef, Bonef - Alexandre Trubert, Trubert - Axelle Dieumegard, Dieumegard - Martin Pezous, Pezous 12:00-12:15 (15min)

› The NAWI Project - Bastien Camillo, iGEM Team Sorbonne_U_Paris - Jeanne Gallix, iGEM Team Sorbonne_U_Paris - Luca Donati, iGEM Team Sorbonne_U_Paris - Vitushanie Yogaranjan, iGEM Team Sorbonne_U_Paris 12:15-12:30 (15min)

› Lighting up the future of agriculture: Fiat Lux, a biosynthetic tool to track pathogenic bacteria in plants - Madeleine Bourseul, Student 12:30-12:45 (15min)

› A synthetic biology toolkit to interface genetic circuits with electronics - Louise Destouches, Centre de Recherches Interdisciplinaires [Paris] - Florence Heng, Centre de Recherches Interdisciplinaires [Paris] 12:45-13:00 (15min)

›12:00 (2h)

Lunch

12:00 - 14:00 (2h)

Lunch

›14:00 (1h30)

Workshop - Synthetic Biology of lactic acid bacteria (Tools for LAB engineering)

14:00 - 15:30 (1h30)

Workshop - Synthetic Biology of lactic acid bacteria (Tools for LAB engineering)

› Use of recombinant Lactic Acid Bacteria to treat infectious diseases: a focus on human papillomavirus (HPV)-induced cancer - LUIS BERMUDEZ, Institut MICALIS, INRAE 14:15-14:30 (15min)

› Genetic toolbox for lactic acid bacteria - Elsa FRISTOT, Centre de Biochimie Structurale [Montpellier] 14:30-14:45 (15min)

› Novel genetic modules encoding high-level antibiotic-free protein expression in probiotic Lactobacillus - Marc Blanch Asensio, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken) - Sourik Dey, Bioprogrammable Materials Group, Leibniz Institute for New Materials (Saarbrücken) 14:45-15:00 (15min)

› The pSIP-system as a tool for genetic engineering of Lactobacillales - Kamilla Wiull, Norwegian University of Life Sciences 15:00-15:15 (15min)

› The phage mv4 recombination system: towards a reprogrammable tool for bacterial genome engineering? - Kevin Debatisse, BLADE - Bacterial Adaptation, Diversity and Engineering 15:15-15:30 (15min)

›15:30 (15min)

Coffee break

15:30 - 15:45 (15min)

Coffee break

›15:45 (1h45)

Workshop - Synthetic Biology of lactic acid bacteria (Applications of recombinant LAB)

15:45 - 17:30 (1h45)

Workshop - Synthetic Biology of lactic acid bacteria (Applications of recombinant LAB)

› Potential use of recombinant biocontained lactococci to deliver the antiprotease elafin in IBD patients - Philippe langella, INRAE, Interactions des Bactéries Commensales et Probiotiques avec l\'Hôte 15:45-16:00 (15min)

› Potential and opportunities for use of recombinant lactic acid bacteria in the gut - Catherine DANIEL, "Cellular Microbiology and Physics of infection" - CIIL - U1019-UMR9017 16:00-16:15 (15min)

› Engineered Lactococcus lactis with simultaneous tumor antigen targeting and proinflammatory cytokine binding ability - Aleš Berlec, Department of Biotechnology, Jožef Stefan Institute, Faculty of Pharmacy, University of Ljubljana 16:15-16:30 (15min)

› Use of recombinant LAB as cDNA delivery vehicle and its applications - jean-marc chatel, INRAE 16:30-16:45 (15min)